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CCL8/MCP-2 Polyclonal Antibody (CAB24871)

SKU:
CAB24871
€129
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CCL8/MCP-2 Polyclonal Antibody
SKU:CAB24871
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-99 of human CCL8/MCP-2 (NP_005614.2).
Sequence:QPDS VSIP ITCC FNVI NRKI PIQR LESY TRIT NIQC PKEA VIFK TKRG KEVC ADPK ERWV RDSM KHLD QIFQ NLKP
Tested Applications:WB
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:CCL8; HC14; MCP-2; MCP2; SCYA10; SCYA8; C-C motif chemokine 8; CCL8/MCP-2
Positive Sample:293T transfected with CCL8/MCP-2
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:11kDa
Observed MW:11kDa

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Purification Method:Affinity purification
Gene ID:6355
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and 293T cells transfected with CCL8/MCP-2 using CCL8/MCP-2 Rabbit pAb(CAB24871) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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