The CCL7 Polyclonal Antibody (CAB16221) is a valuable tool for research involving CCL7, a chemokine involved in the regulation of immune responses and inflammation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CCL7 protein, this antibody enables detection and analysis in various cell types, making it an ideal choice for studies in immunology, inflammation, and cancer research.
CCL7, also known as monocyte-specific chemokine 3 (MCP-3), plays a crucial role in recruiting monocytes and other immune cells to sites of inflammation. Understanding the function of CCL7 is essential for studying the pathogenesis of diseases such as cancer, autoimmune disorders, and inflammatory conditions. Research on CCL7 can provide valuable insights into the development of novel therapies targeting inflammatory pathways and immune responses in various disease contexts.
Product Name:
CCL7 Polyclonal Antibody
SKU:
CAB16221
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human CCL7 (NP_006264.2).
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Purification Method:
Affinity purification
Gene ID:
6354
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CCL7 Rabbit pAb (CAB16221) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
