The CCL4 Polyclonal Antibody (CAB1671) is a valuable tool for researchers studying CCL4, a chemokine involved in inflammatory responses and immune cell recruitment. Produced in rabbits, this antibody has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CCL4 protein, researchers can accurately detect and analyze CCL4 levels in various cell types, making it ideal for studies in immunology, inflammation, and cancer research.CCL4, also known as MIP-1β, is a key player in immune responses, functioning to attract and activate immune cells such as monocytes, T cells, and dendritic cells.
Its role in mediating inflammatory processes and initiating immune cell migration makes it a crucial target for research on various diseases, including inflammatory disorders, infectious diseases, and cancer. Understanding the function of CCL4 can provide valuable insights into the mechanisms underlying immune response regulation and potential therapeutic strategies.
Product Name:
CCL4 Rabbit Polyclonal Antibody
SKU:
CAB1671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-92 of human CCL4 (NP_002975.1).
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions.
Purification Method:
Affinity purification
Gene ID:
6351
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CCL4 antibody (CAB1671) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
