The CCL3L1 Polyclonal Antibody (CAB2852) is a valuable tool for researchers studying CCL3L1, a chemokine involved in immune responses and inflammation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CCL3L1 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in immunology and inflammatory conditions.CCL3L1 is known for its role in recruiting immune cells to sites of inflammation and infection, making it a key player in the immune response.
Research on CCL3L1 has shown its potential implications in diseases such as cancer, infectious diseases, and autoimmune disorders. Understanding the function of CCL3L1 is essential for developing targeted therapies that modulate immune responses in these conditions.Overall, the CCL3L1 Polyclonal Antibody (CAB2852) is a valuable tool for researchers investigating the role of CCL3L1 in immune responses and inflammatory conditions, providing crucial insights for the development of novel treatments and therapies.
Product Name:
CCL3L1 Rabbit Polyclonal Antibody
SKU:
CAB2852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-93 of human CCL3L1 (NP_066286.1).
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6349
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of B-cell cells, using CCL3L1 antibody (CAB2852) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
