The CCL25 Polyclonal Antibody (CAB2685) is a valuable tool for researchers studying CCL25, a chemokine that plays a crucial role in immune cell trafficking and inflammation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CCL25 protein, this antibody allows for the detection and analysis of CCL25 in various cell types, making it an essential reagent for studies in immunology, inflammation, and cancer research.CCL25, also known as thymus-expressed chemokine, is involved in the recruitment of immune cells to specific tissues and plays a key role in directing T cell migration to the thymus and gut.
Its function in immune cell homing and inflammation makes it a promising target for research into conditions such as inflammatory bowel disease, allergy, and cancer. By understanding the role of CCL25 in immune cell recruitment and activation, researchers can gain insights that may lead to the development of novel therapeutic strategies for treating inflammatory and immune-related diseases.
Product Name:
CCL25 Rabbit Polyclonal Antibody
SKU:
CAB2685
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-150 of human CCL25 (NP_005615.2).
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6370
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with CCL25, using CCL25 Rabbit pAb (CAB2685) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.5s.
