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Ccl25 Antibody (PACO32668)

SKU:
PACO32668
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

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Ccl25 Antibody (PACO32668)

The CCL25 Antibody (PAC032668) is a polyclonal antibody designed for research involving CCL25, a chemokine protein implicated in immune cell trafficking and inflammation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the CCL25 protein, allowing for precise detection and analysis in various cell types, making it an excellent tool for studies in immunology and inflammation research.CCL25, also known as thymus-expressed chemokine, plays a crucial role in directing immune cells to the thymus and small intestine, where it regulates immune responses and maintains immune homeostasis.

Its involvement in inflammatory processes and immune cell migration makes it a valuable target for research into diseases like inflammatory bowel disease, asthma, and cancer. A deeper understanding of the functions of CCL25 is essential for developing targeted therapies that modulate immune responses in these pathologies.

Antibody Name:Ccl25 Antibody (PACO32668)
Antibody SKU:PACO32668
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Mouse
Immunogen:Recombinant Mouse C-C motif chemokine 25 protein (25-144AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9.
Synonyms:C-C motif chemokine 25 (Chemokine TECK) (Small-inducible cytokine A25) (Thymus-expressed chemokine), Ccl25, Scya25 Teck
UniProt Protein Function:CCL25: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Belongs to the intercrine beta (chemokine CC) family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function:protein binding; chemokine activity; chemokine receptor binding; CCR10 chemokine receptor binding; cytokine activity

Biological Process: G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; positive regulation of cell-matrix adhesion; chemotaxis; leukocyte migration

UniProt Code:O35903
NCBI GenInfo Identifier:3122923
NCBI Gene ID:20300
NCBI Accession:O35903.1
Molecular Weight:16,714 Da
NCBI Full Name:C-C motif chemokine 25
UniProt Protein Name:C-C motif chemokine 25
UniProt Synonym Protein Names:Chemokine TECK; Small-inducible cytokine A25; Thymus-expressed chemokine
Protein Family:C-C motif chemokine
UniProt Gene Name:Ccl25  
UniProt Entry Name:CCL25_MOUSE

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