The CCL1 Polyclonal Antibody is a versatile tool for researchers studying CCL1, a chemokine involved in inflammation and immune response. This antibody, produced in rabbits, offers high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CCL1 protein, researchers can easily detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.CCL1, also known as I-309, plays a crucial role in recruiting immune cells to sites of inflammation and infection.
Understanding the function of CCL1 is essential for unraveling the complexities of the immune response and developing targeted therapies for inflammatory conditions, autoimmune diseases, and cancer. By utilizing the CCL1 Polyclonal Antibody, researchers can gain insights into the role of this chemokine in disease pathogenesis and potentially identify new therapeutic targets for intervention.
Product Name:
CCL1 Polyclonal Antibody
SKU:
CAB10670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-96 of human CCL1 (NP_002972.1).
Sequence:
KSMQ VPFS RCCF SFAE QEIP LRAI LCYR NTSS ICSN EGLI FKLK RGKE ACAL DTVG WVQR HRKM LRHC PSKR K
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
P500; SISe; TCA3; I-309; SCYA1; CCL1
Positive Sample:
RPMI 8226
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
11kDa
Observed MW:
14kDa
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
Purification Method:
Affinity purification
Gene ID:
6346
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from RPMI 8226 cells, using CCL1 Rabbit pAb (CAB10670) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
