The CCKBR Polyclonal Antibody (CAB14567) is a valuable tool for researchers studying the cholecystokinin B receptor (CCKBR). This receptor is involved in various physiological processes, including appetite regulation, gastric acid secretion, and neurotransmission. The antibody, produced in rabbits, is highly specific to CCKBR and has been validated for use in Western blot applications.CCKBR is known to play a role in conditions such as obesity, gastrointestinal disorders, and psychiatric disorders, making it a promising target for therapeutic development.
By using the CCKBR Polyclonal Antibody, researchers can analyze the expression and localization of CCKBR in different cell types and tissues, aiding in the understanding of its function in health and disease.Overall, the CCKBR Polyclonal Antibody is a reliable tool for investigating the role of CCKBR in various physiological processes and diseases, contributing to advancements in biomedical research and potential therapeutic strategies.
Product Name:
CCKBR Rabbit Polyclonal Antibody
SKU:
CAB14567
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-335 of human CCKBR (NP_795344.1).
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Purification Method:
Affinity purification
Gene ID:
887
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCKBR Rabbit pAb (CAB14567) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
