The CCKAR Polyclonal Antibody (CAB16799) is a valuable tool for researchers studying the cholecystokinin A receptor (CCKAR), a G-protein coupled receptor involved in the regulation of various physiological processes, including digestion and appetite control. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of CCKAR expression in different cell types.
By targeting the CCKAR protein, researchers can gain insights into its role in gastrointestinal functioning, satiety signaling, and potential therapeutic applications in conditions related to appetite regulation and digestion. This antibody is ideal for studies in gastroenterology, obesity research, and pharmacology, providing a valuable tool for understanding the complex mechanisms underlying CCKAR function.
Product Name:
CCKAR Rabbit Polyclonal Antibody
SKU:
CAB16799
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CCKAR (NP_000721.1).
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
Purification Method:
Affinity purification
Gene ID:
886
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCKAR Rabbit pAb (CAB16799) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.