The CCK Rabbit Polyclonal Antibody (CAB1759) is a valuable tool for researchers studying Cholecystokinin (CCK), a peptide hormone involved in the regulation of digestion and appetite. This antibody is raised in rabbits and has high reactivity with human samples, making it ideal for use in immunohistochemistry and ELISA applications. By binding specifically to the CCK molecule, this antibody enables the detection and analysis of CCK expression in various tissues and cells.CCK is known to play a key role in the stimulation of pancreatic enzyme secretion and the contraction of the gallbladder, making it a crucial player in the digestive process.
Additionally, CCK has been implicated in the regulation of food intake and satiety, making it a potential target for research into obesity and eating disorders. Understanding the expression and function of CCK in different physiological and pathological contexts is essential for unraveling its role in these processes and developing targeted therapies.
Product Name:
CCK Polyclonal Antibody
SKU:
CAB1759
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-115 of human CCK (NP_000720.1).
This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
885
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CCK antibody (CAB1759) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
