The CCDC88A Polyclonal Antibody (CAB16132) is a valuable tool for researchers studying CCDC88A, a protein involved in cell signaling and migration processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot applications. By selectively binding to the CCDC88A protein, this antibody enables accurate detection and analysis of CCDC88A expression in various cell types.CCDC88A, also known as Coiled-coil domain-containing protein 88A, is implicated in various cellular functions, including cell adhesion and migration.
Its role in regulating signaling pathways involved in cell behavior makes it a promising target for studies in cancer research and developmental biology. The CCDC88A Polyclonal Antibody offers researchers a reliable tool for investigating the function and localization of CCDC88A, contributing to a better understanding of its impact on cellular processes.
Product Name:
CCDC88A Rabbit Polyclonal Antibody
SKU:
CAB16132
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1571-1870 of human CCDC88A (NP_001129069.1).
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
55704
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCDC88A Rabbit pAb (CAB16132) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
