The CCDC50 Rabbit Polyclonal Antibody (CAB17836) is a valuable tool for researchers studying CCDC50, a protein involved in various cellular processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting CCDC50 in human samples, making it suitable for Western blot applications. By binding to the CCDC50 protein, this antibody enables the visualization and analysis of CCDC50 in different cell types, making it an essential reagent for studies in molecular biology and cell signaling.
CCDC50, also known as coiled-coil domain-containing protein 50, plays a crucial role in cellular functions such as cell division and intracellular transport. Its implication in these processes makes it a potential target for research in diverse areas such as cancer biology, neurobiology, and developmental biology. Understanding the function of CCDC50 can provide insights into mechanisms underlying various diseases and may lead to the development of novel therapeutic strategies targeting this protein.
Product Name:
CCDC50 Rabbit Polyclonal Antibody
SKU:
CAB17836
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-147 of human CCDC50 (NP_777568.1).
This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
152137
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCDC50 Rabbit pAb (CAB17836) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
