The CCAR1 Polyclonal Antibody (CAB6334) is a valuable tool for researchers studying CCAR1, a protein involved in cell cycle regulation and DNA damage response. This antibody, raised in rabbits, exhibits high specificity and sensitivity for human samples, making it a reliable choice for Western blot applications. By targeting the CCAR1 protein, this antibody facilitates the detection and analysis of CCAR1 expression in various cell types, making it ideal for research in areas such as cell biology, oncology, and genomics. CCAR1, also known as cell cycle and apoptosis regulator protein 1, plays a crucial role in coordinating cellular processes such as DNA replication and repair.
Dysregulation of CCAR1 has been implicated in cancer development and progression, highlighting its potential as a therapeutic target. By studying CCAR1 expression and function, researchers can gain insights into its role in tumorigenesis and potentially identify new strategies for cancer treatment. Overall, the CCAR1 Polyclonal Antibody (CAB6334) offers a reliable tool for investigating the biological functions of CCAR1 and its implications in various disease processes. Its specificity and sensitivity make it an essential resource for researchers aiming to deepen their understanding of CCAR1 biology and its potential applications in clinical research.
Product Name:
CCAR1 Rabbit Polyclonal Antibody
SKU:
CAB6334
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CCAR1 (NP_060707.2).
WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
CCAR1
Positive Sample:
HepG2,Mouse testis,Rat spleen
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, perinuclear region.
Calculated MW:
133kDa
Observed MW:
132kDa
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor coactivator activity; and transcription corepressor activity. Involved in positive regulation of cell migration and positive regulation of cell population proliferation. Acts upstream of or within positive regulation of apoptotic process. Located in nuclear envelope lumen.
Purification Method:
Affinity purification
Gene ID:
55749
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using CCAR1 Rabbit pAb (CAB6334) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
