The CCAR1 Polyclonal Antibody (CAB13595) is a valuable tool for researchers studying CCAR1, a protein involved in cell growth and differentiation. This antibody, produced in rabbits, is highly specific for CCAR1 and is validated for use in various applications, including Western blot and immunohistochemistry. By binding to CCAR1, this antibody allows for the detection and analysis of the protein in different cell types, making it an essential component for studies in cancer research and cell biology.
CCAR1, also known as cell cycle and apoptosis regulator protein 1, plays a critical role in regulating cellular processes that are essential for normal cell function. Its involvement in cell growth and survival pathways makes it a promising target for research into cancer and other diseases characterized by abnormal cell proliferation. Understanding the function of CCAR1 is crucial for developing targeted therapies that can potentially inhibit or modulate its activity in disease settings.
Product Name:
CCAR1 Rabbit Polyclonal Antibody
SKU:
CAB13595
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CCAR1 (NP_060707.2).
WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
CCAR1
Positive Sample:
A-549,Mouse brain,Mouse testis,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, perinuclear region.
Calculated MW:
133kDa
Observed MW:
132kDa
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor coactivator activity; and transcription corepressor activity. Involved in positive regulation of cell migration and positive regulation of cell population proliferation. Acts upstream of or within positive regulation of apoptotic process. Located in nuclear envelope lumen.
Purification Method:
Affinity purification
Gene ID:
55749
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCAR1 Rabbit pAb (CAB13595) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
