The CC2D1A Polyclonal Antibody (CAB4800) is a valuable tool for researchers studying CC2D1A, a protein involved in various cellular processes such as endocytosis, membrane trafficking, and vesicle formation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.CC2D1A is known to interact with proteins involved in endosomal trafficking and plays a role in regulating gene expression. Dysfunction of CC2D1A has been linked to intellectual disabilities and neurodevelopmental disorders.
By targeting the CC2D1A protein, researchers can gain insight into its function and potential implications in disease pathology.The CC2D1A Polyclonal Antibody is a versatile tool for investigating the role of CC2D1A in various cellular pathways and diseases, making it a valuable asset for studies in cell biology and neurology research. Its specificity and sensitivity make it ideal for detecting CC2D1A protein levels in different cell types and tissues, enabling researchers to further our understanding of this important protein.
Product Name:
CC2D1A Rabbit Polyclonal Antibody
SKU:
CAB4800
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CC2D1A (NP_060191.3).
Sequence:
MHKR KGPP GPPG RGAA AARQ LGLL VDLS PDGL MIPE DGAN DEEL EAEF LALV GGQP PALE KLKG KGPL PMEA IEKM ASLC MRDP DEDE EEGT DEDD LEAD DDLL AELN EVLG EEQK ASET PPPV AQPK PEAP HPGL ETTL QERL ALYQ TA
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in a nonsyndromic form of cognitive disability (MRT3).
Purification Method:
Affinity purification
Gene ID:
54862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CC2D1A Rabbit pAb (CAB4800) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
