The CBX8 Polyclonal Antibody (CAB6222) is a valuable tool for researchers studying the CBX8 protein, a key player in epigenetic regulation and chromatin remodeling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.CBX8 is a crucial component of the polycomb repressive complex 1 (PRC1), which plays a key role in gene silencing and chromatin compaction. By targeting CBX8, researchers can investigate its function in various cellular processes, such as gene expression regulation, cell differentiation, and development.
The CBX8 Polyclonal Antibody enables precise detection and analysis of CBX8 protein levels in different cell types, making it an essential tool for studies in genetics, molecular biology, and cancer research. Understanding the role of CBX8 in epigenetic regulation may lead to new therapeutic approaches for diseases associated with aberrant gene expression and chromatin alterations.
Product Name:
CBX8 Rabbit Polyclonal Antibody
SKU:
CAB6222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human CBX8 (NP_065700.1).
Enables methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in chromatin and nucleoplasm. Part of PRC1 complex. Biomarker of esophagus squamous cell carcinoma and glioblastoma.
Purification Method:
Affinity purification
Gene ID:
57332
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CBX8 Rabbit pAb (CAB6222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
