The CBX6 Polyclonal Antibody (CAB5533) is a crucial tool for researchers studying the CBX6 protein, a key player in chromatin organization and gene regulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CBX6 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in epigenetics, gene expression, and developmental biology.CBX6, a member of the Polycomb group proteins, functions as a transcriptional repressor by regulating chromatin structure and gene silencing.
Its involvement in chromatin remodeling makes it a promising target for studies on cell differentiation, embryonic development, and disease mechanisms. Research on CBX6 can provide insights into epigenetic regulation and potential therapeutic strategies for conditions such as cancer, neurological disorders, and developmental abnormalities.Overall, the CBX6 Polyclonal Antibody is a valuable tool for scientists aiming to unravel the roles of CBX6 in gene expression and chromatin dynamics, offering new opportunities for advancing our understanding of cellular processes and disease pathogenesis.
Product Name:
CBX6 Rabbit Polyclonal Antibody
SKU:
CAB5533
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP_055107.3).
Predicted to enable single-stranded RNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of PcG protein complex. Biomarker of glioblastoma.
Purification Method:
Affinity purification
Gene ID:
23466
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using CBX6 Rabbit pAb (CAB5533) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
