The CBR4 Polyclonal Antibody (CAB5069) is a valuable tool for researchers studying the CBR4 protein, a key player in various cellular processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the CBR4 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in fields such as pharmacology, neuroscience, and cancer research.CBR4, also known as carbonyl reductase 4, is involved in the detoxification of reactive carbonyl compounds and plays a critical role in drug metabolism and oxidative stress response.
Its implications in cellular functions and disease pathogenesis make it a promising target for therapeutic interventions in conditions such as neurodegenerative disorders, cancer, and metabolic diseases. Further exploration of CBR4 function is essential for advancing our understanding of these processes and developing targeted therapies for effective disease management.
Product Name:
CBR4 Rabbit Polyclonal Antibody
SKU:
CAB5069
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human CBR4 (NP_116172.2).
Enables several functions, including 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NADPH binding activity; and NADPH dehydrogenase (quinone) activity. Involved in fatty acid biosynthetic process; glycoside metabolic process; and protein tetramerization. Located in mitochondrial matrix. Part of oxidoreductase complex.
Purification Method:
Affinity purification
Gene ID:
84869
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CBR4 antibody (CAB5069) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
