null

CBR1 PAT2D6AT Monoclonal Antibody [PAT2D6AT] (CPAB0203)

SKU:
CPAB0203
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2D6AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

CBR1 PAT2D6AT Monoclonal Antibody [PAT2D6AT] (CPAB0203)

The CBR1/PAT2D6AT Antibody (CPAB0203) is a polyclonal antibody designed for research involving CBR1 and PAT2D6AT, enzymes involved in drug metabolism and detoxification processes in the liver. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications including Western blot and immunohistochemistry.CBR1 and PAT2D6AT are key enzymes in the cytochrome P450 system, responsible for metabolizing a wide range of drugs and xenobiotics in the body. Understanding the expression and activity of these enzymes is crucial for predicting drug interactions, toxicity, and therapeutic efficacy.

This antibody binds specifically to CBR1 and PAT2D6AT proteins, allowing for accurate detection and analysis in research related to drug metabolism, pharmacology, and toxicology.The CBR1/PAT2D6AT Antibody (CPAB0203) is a valuable tool for researchers studying drug metabolism, pharmacokinetics, and drug-drug interactions. Its high specificity and sensitivity make it ideal for detecting subtle changes in enzyme expression and activity, paving the way for advancements in personalized medicine and drug development.

Product Name:CBR1 PAT2D6AT Antibody
Product Sku:CPAB0203
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CBR1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CBR1 amino acids 1-277 purified from Ecoli.
Clone:PAT2D6AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:CBR1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:CBR1 is one of numerous monomeric, NADPH-dependent oxidoreductases having ubiquistly specificity for carbonyl compounds. CBR1 is broadly distributed in human tissues. CBR1 metabolizes toxic environmental quinones and pharmacological relevant substrates such as the anticancer doxorubicin. CBR1 converts prostaglandin E2 to prostaglandin F2-alpha.
Synonyms:CBR, hCBR1, SDR21C1, CBR1, Carbonyl reductase [NADPH] 1, NADPH-dependent carbonyl reductase 1, Prostaglandin-E(2) 9-reductase, Prostaglandin 9-ketoreductase, 15-hydroxyprostaglandin dehydrogenase [NADP+], CRN.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products