The CBP80 Polyclonal Antibody (CAB13939) is a valuable tool for researchers studying CBP80, a protein involved in mRNA processing and export. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CBP80 protein, researchers can detect and analyze CBP80 expression in various cell types, making it an ideal choice for studies in molecular biology and gene regulation.CBP80 is a key player in the mRNA export pathway, playing a crucial role in gene expression and protein synthesis. Understanding the function of CBP80 is essential for unraveling the complexities of gene regulation and RNA processing.
Research into CBP80 has implications for advancing our knowledge of various diseases, including cancer and genetic disorders, and may lead to the development of new therapeutic approaches targeting mRNA processing pathways.Overall, the CBP80 Polyclonal Antibody (CAB13939) provides researchers with a reliable tool for investigating the role of CBP80 in gene expression and mRNA export processes. Its specificity and sensitivity make it a valuable asset for studies aiming to unravel the mysteries of cellular and molecular biology.
Product Name:
CBP80 Rabbit Polyclonal Antibody
SKU:
CAB13939
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CBP80 (NP_002477.1).
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
Purification Method:
Affinity purification
Gene ID:
4686
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CBP80 Rabbit pAb (CAB13939) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
