The Cblc Polyclonal Antiboy (CAB7789) is a crucial tool for researchers studying Cblc, a signaling protein involved in cellular processes such as growth and metabolism. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the Cblc protein, this antibody enables precise detection and analysis in various cell types, making it an invaluable resource for studies in cell biology and cancer research.Cblc is known to play a key role in regulating intracellular signaling pathways that control cell growth and differentiation. Dysregulation of Cblc expression or function has been implicated in various diseases, including cancer and metabolic disorders.
By elucidating the mechanisms by which Cblc impacts cellular processes, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets.The Cblc Polyclonal Antibody offers researchers a reliable tool for investigating the role of Cblc in health and disease. Its superior reactivity and specificity make it an ideal choice for studies aimed at understanding the intricate signaling networks that govern cellular function. By utilizing this antibody in their research, scientists can uncover novel insights into the molecular pathways regulated by Cblc, paving the way for the development of targeted therapies for a range of diseases.
Product Name:
CBLC Rabbit Polyclonal Antibody
SKU:
CAB7789
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-474 of human CBLC (NP_036248.3).
This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
23624
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CBLC antibody (CAB7789) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 90s.
