CBFA2T3 Rabbit Polyclonal Antibody (CAB14712)
- SKU:
- CAB14712
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | CBFA2T3 Rabbit Polyclonal Antibody |
SKU: | CAB14712 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 593-653 of human CBFA2T3 (NP_005178.4). |
Sequence: | GQSL QGPT AVVA DPVP GPPE AAHS LGPS LPVG AASP SEAG SAGP SRPG SPSP PGPL DTVP R |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ETO2; MTG16; MTGR2; ZMYND4; RUNX1T3; CBFA2T3 |
Positive Sample: | Jurkat,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Nucleus, nucleolus, nucleoplasm. |
Calculated MW: | 71kDa |
Observed MW: | 75kDa |
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 863 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |