Caveolin-3 Rabbit Polyclonal Antibody (CAB8089)
- SKU:
- CAB8089
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Caveolin-3 Rabbit Polyclonal Antibody |
SKU: | CAB8089 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human Caveolin-3 (NP_001225.1). |
Sequence: | MMAE EHTD LEAQ IVKD IHCK EIDL VNRD PKNI NEDI VKVD FEDV IAEP VGTY SFDG VWKV SYTT FTVS KYWC YRLL STLL GVPL ALLW GFLF ACIS FCHI WAVV PCIK SYLI EIQC ISHI YSLC IRTF CNPL FAAL GQVC SSIK VVLR KEV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | LQT9; MPDT; RMD2; VIP21; LGMD1C; VIP-21; Caveolin-3 |
Positive Sample: | BT-474,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Golgi apparatus membrane, Membrane, Peripheral membrane protein, caveola. |
Calculated MW: | 17kDa |
Observed MW: | 17kDa |
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Purification Method: | Affinity purification |
Gene ID: | 859 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |