The Caveolin-2 Rabbit Monoclonal Antibody (CAB4890) is a cutting-edge research tool designed for the study of Caveolin-2, a critical protein involved in cellular signaling, lipid metabolism, and vesicular trafficking. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity for detecting Caveolin-2 in a variety of experimental settings.Caveolin-2, a key component of caveolae, plays a crucial role in the regulation of cell signaling pathways and membrane organization. By targeting Caveolin-2, researchers can gain valuable insights into its functions and implications in various biological processes.
This antibody is recommended for use in techniques such as Western blotting, immunofluorescence, and immunohistochemistry to visualize Caveolin-2 expression and localization within cells and tissues.With its ability to specifically recognize Caveolin-2 in different cellular contexts, the CAB4890 antibody is an invaluable tool for investigating the role of Caveolin-2 in normal physiology and disease states. Its versatility and reliability make it an essential component of studies focusing on cellular signaling, lipid biology, and membrane dynamics. Uncover the mysteries of Caveolin-2 with the precision and accuracy of the CAB4890 antibody.
Product Name:
Caveolin-2 Rabbit Monoclonal Antibody
SKU:
CAB4890
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Caveolin-2 (P51636).
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).
Purification Method:
Affinity purification
Gene ID:
858
Clone Number:
ARC0323
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using Caveolin-2 Rabbit mAb (CAB4890) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
