Caveolin-3 Rabbit Polyclonal Antibody (CAB12769)
- SKU:
- CAB12769
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Caveolin-3 Rabbit Polyclonal Antibody |
SKU: | CAB12769 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Caveolin-3 (NP_001225.1). |
Sequence: | MMAE EHTD LEAQ IVKD IHCK EIDL VNRD PKNI NEDI VKVD FEDV IAEP VGTY SFDG VWKV SYTT FTVS KYWC YRLL STLL GVPL ALLW GFLF ACIS FCHI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LQT9; MPDT; RMD2; VIP21; LGMD1C; VIP-21; Caveolin-3 |
Positive Sample: | Mouse heart,Rat skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Golgi apparatus membrane, Membrane, Peripheral membrane protein, caveola. |
Calculated MW: | 17kDa |
Observed MW: | 17kDa |
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Purification Method: | Affinity purification |
Gene ID: | 859 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |