The CATSPER3 Polyclonal Antibody (PACO15940) is a valuable tool for research involving CATSPER3, a protein involved in sperm cell function and fertility. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to the CATSPER3 protein, this antibody allows for the precise detection and analysis of CATSPER3 in various cell types, making it ideal for studies in reproductive biology and infertility research.CATSPER3 is a key component of the CATSPER ion channel complex, which plays a critical role in regulating calcium influx in sperm cells, ultimately influencing sperm motility and fertilization potential.
Understanding the function of CATSPER3 is essential for unraveling the mechanisms underlying male infertility and developing new treatments for reproductive disorders.With its high specificity and sensitivity, the CATSPER3 Polyclonal Antibody (PACO15940) is a valuable tool for researchers investigating the role of CATSPER3 in fertility and reproductive health. Its ability to detect and analyze CATSPER3 in human samples makes it an essential asset for studies aiming to uncover new insights into male infertility and develop novel therapeutic strategies.
Antibody Name:
CATSPER3 Antibody (PACO15940)
Antibody SKU:
PACO15940
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Fusion protein of human CATSPER3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15940(CATSPER3 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15940(CATSPER3 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
CatSper3, is a protein which in humans is encoded by the CATSPER3 gene. CatSper3 is a member of thecation channels of sperm family of proteins. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells. Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
