CTSK Rabbit Polyclonal Antibody (CAB1782)
- SKU:
- CAB1782
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CTSK Rabbit Polyclonal Antibody |
SKU: | CAB1782 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1). |
Sequence: | APDS VDYR KKGY VTPV KNQG QCGS CWAF SSVG ALEG QLKK KTGK LLNL SPQN LVDC VSEN DGCG GGYM TNAF QYVQ KNRG IDSE DAYP YVGQ EESC MYNP TGKA AKCR GYRE IPEG NEKA LKRA VARV GPVS VAID ASLT SFQF YSKG VYYD ESCN SDNL NHAV LAVG YGIQ KGNK HWII KNSW GENW GNKG YILM ARNK NNAC GIAN LASF PKM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2; CTSK |
Positive Sample: | SK-MEL-28,U-87MG,MG-63 |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome. |
Calculated MW: | 37kDa |
Observed MW: | 26kDa/37kDa |
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
Purification Method: | Affinity purification |
Gene ID: | 1513 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |