The Cathepsin G Monoclonal Antibody (CAB22048) is a cutting-edge research tool designed for the study of Cathepsin G, a serine protease enzyme involved in immune response and inflammation. This monoclonal antibody, produced through specialized techniques, offers high specificity and sensitivity for detecting Cathepsin G in various biological samples.Cathepsin G is known for its role in immune defense, as it is released by neutrophils to help combat bacterial infections. Studies have also implicated Cathepsin G in inflammatory diseases, such as arthritis and atherosclerosis, making it a promising target for therapeutic development. This antibody allows for the precise visualization and quantification of Cathepsin G in experimental settings, enabling researchers to unravel its functions and potential implications in different disease contexts.
With its proven efficacy in techniques like Western blotting and immunohistochemistry, the Cathepsin G Monoclonal Antibody (CAB22048) facilitates accurate and reliable analysis of Cathepsin G expression and localization. Its versatility and sensitivity make it an invaluable tool for investigations in immunology, inflammation, and diseases where Cathepsin G is implicated. Upgrade your research capabilities with this advanced antibody and unlock new insights into the role of Cathepsin G in health and disease.
Product Name:
Cathepsin G Monoclonal Antibody
SKU:
CAB22048
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 156-255 of human Cathepsin G (NP_001902.1).
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Purification Method:
Affinity purification
Gene ID:
1511
Clone Number:
ARC54792
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of THP-1 cells, using Cathepsin G antibody (CAB22048) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
