Cathepsin D Rabbit Polyclonal Antibody (CAB1594)
- SKU:
- CAB1594
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Cathepsin D Rabbit Polyclonal Antibody |
SKU: | CAB1594 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-412 of human Cathepsin D (NP_001900.1). |
Sequence: | GPIP EVLK NYMD AQYY GEIG IGTP PQCF TVVF DTGS SNLW VPSI HCKL LDIA CWIH HKYN SDKS STYV KNGT SFDI HYGS GSLS GYLS QDTV SVPC QSAS SASA LGGV KVER QVFG EATK QPGI TFIA AKFD GILG MAYP RISV NNVL PVFD NLMQ QKLV DQNI FSFY LSRD PDAQ PGGE LMLG GTDS KYYK GSLS YLNV TRKA YWQV HLDQ VEVA SGLT LCKE GCEA IVDT GTSL MVGP VDEV RELQ KAIG AVPL IQGE YMIP CEKV STLP AITL KLGG KGYK LSPE DYTL KVSQ AGKT LCLS GFMG MDIP PPSG PLWI LGDV FIGR YYTV FDRD NNRV GFAE AARL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CPSD; CLN10; HEL-S-130P; Cathepsin D |
Positive Sample: | A-549,Mouse kidney,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome, Melanosome, Secreted, extracellular space. |
Calculated MW: | 45kDa |
Observed MW: | 53kDa |
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
Purification Method: | Affinity purification |
Gene ID: | 1509 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |