The Catenin p120 Polyclonal Antibody (CAB10006) is a valuable tool for researchers studying the role of p120 catenin, a key protein involved in cell adhesion and signaling pathways. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to p120 catenin, researchers can accurately detect and analyze this protein in various cell types, making it an ideal choice for studies in cell biology and cancer research.p120 catenin is a crucial component of adherens junctions, which play a critical role in maintaining tissue integrity and regulating cell behavior.
Dysregulation of p120 catenin has been implicated in various diseases, including cancer, where its loss or altered expression can impact tumor progression and metastasis. Understanding the function and regulation of p120 catenin is essential for unraveling the mechanisms underlying these diseases and developing targeted therapies.Overall, the Catenin p120 Polyclonal Antibody provides researchers with a reliable tool for investigating the involvement of p120 catenin in cellular processes and disease pathways, ultimately advancing our understanding of its potential as a therapeutic target.
Product Name:
δ-Catenin/p120 Catenin Polyclonal Antibody
SKU:
CAB21371
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 573-832 of human δ-Catenin/p120 Catenin (NP_001078938.1).
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.
Purification Method:
Affinity purification
Gene ID:
1500
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using δ-Catenin/p120 Catenin Rabbit pAb (CAB21371) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
