CAST Rabbit Polyclonal Antibody (CAB16790)
- SKU:
- CAB16790
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CAST Rabbit Polyclonal Antibody |
SKU: | CAB16790 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 406-695 of human CAST (NP_001177371.1). |
Sequence: | PPEP ATLK GTVP DDAV EALA DSLG KKEA DPED GKPV MDKV KEKA KEED REKL GEKE ETIP PDYR LEEV KDKD GKPL LPKE SKEQ LPPM SEDF LLDA LSED FSGP QNAS SLKF EDAK LAAA ISEV VSQT PAST TQAG APPR DTSQ SDKD LDDA LDKL SDSL GQRQ PDPD ENKP MEDK VKEK AKAE HRDK LGER DDTI PPEY RHLL DDNG QDKP VKPP TKKS EDSK KPAD DQDP IDAL SGDL DSCP STTE TSQN TAKD KCKK AASS SKAP KNGG KAKD SAKT TEET SKPK DD |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | BS-17; PLACK; CAST |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, endoplasmic reticulum |
Calculated MW: | 77kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 831 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |