Caspase-8 Rabbit Polyclonal Antibody (CAB11324)
- SKU:
- CAB11324
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Caspase-8 Rabbit Polyclonal Antibody |
SKU: | CAB11324 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 4-480 of mouse Caspase 8 (NP_033942.1). |
Sequence: | QSCL YAIA EELG SEDL AALK FLCL DYIP HKKQ ETIE DAQK LFLR LREK GMLE EGNL SFLK ELLF HISR WDLL VNFL DCNR EEMV RELR DPDN AQIS PYRV MLFK LSEE VSEL ELRS FKFL LNNE IPKC KLED DLSL LEIF VEME KRTM LAEN NLET LKSI CDQV NKSL LGKI EDYE RSST ERRM SLEG REEL PPSV LDEM SLKM AELC DSPR EQDS ESRT SDKV YQMK NKPR GYCL IINN HDFS KARE DITQ LRKM KDRK GTDC DKEA LSKT FKEL HFEI VSYD DCTA NEIH EILE GYQS ADHK NKDC FICC ILSH GDKG VVYG TDGK EASI YDLT SYFT GSKC PSLS GKPK IFFI QACQ GSNF QKGV PDEA GFEQ QNHT LEVD SSSH KNYI PDEA DFLL GMAT VKNC VSYR DPVN GTWY IQSL CQSL RERC PQGD DILS ILTG VNYD VSNK DDRR NKGK QMPQ PTFT LRKK LFFP P |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | MACH; Mch5; FLICE; CASP-8; Caspase-8 |
Positive Sample: | THP-1,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 55kDa |
Observed MW: | 57kDa |
This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method: | Affinity purification |
Gene ID: | 12370 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |