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Caspase-7 Rabbit Polyclonal Antibody (CAB1524)

SKU:
CAB1524
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-Caspase-7 Antibody CAB1524
  • Cell Death Antibodies 1 Anti-Caspase-7 Antibody CAB1524
  • Cell Death Antibodies 1 Anti-Caspase-7 Antibody CAB1524
  • Cell Death Antibodies 1 Anti-Caspase-7 Antibody CAB1524
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Caspase-7 Rabbit Polyclonal Antibody
SKU:CAB1524
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Caspase-7 (NP_001218.1).
Sequence:IYGK DGVT PIKD LTAH FRGD RCKT LLEK PKLF FIQA CRGT ELDD GIQA DSGP INDT DANP RYKI PVEA DFLF AYST VPGY YSWR SPGR GSWF VQAL CSIL E
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; Caspase-7
Positive Sample:Mouse liver,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:34kDa
Observed MW:35kDa

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Purification Method:Affinity purification
Gene ID:840
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat liver, using Caspase-7 Rabbit pAb (CAB1524) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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