The Caspase-6 Polyclonal Antibody (CAB1784) is a valuable tool for researchers studying caspase-6, a crucial enzyme involved in apoptosis and inflammation. This antibody is produced in rabbits and is highly specific to human samples, making it an ideal choice for Western blot applications. By binding to the caspase-6 protein, this antibody enables precise detection and analysis in a variety of cell types, making it particularly useful in immunology and cancer research.Caspase-6 is known for its role in programmed cell death, making it a key player in various diseases, including cancer and neurodegenerative disorders.
By understanding the function of caspase-6, researchers can gain insights into potential therapeutic targets for treating these conditions. The Caspase-6 Polyclonal Antibody is a valuable tool for investigating the mechanisms of apoptosis and inflammation, leading to advancements in medical research and drug development.
Product Name:
Caspase-6 Rabbit Polyclonal Antibody
SKU:
CAB1784
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 194-293 of human Caspase-6 (NP_001217.2).
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
839
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Caspase-6 antibody (CAB1784) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
