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Caspase-6 Monoclonal Antibody (CAB24004)

SKU:
CAB24004
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

Caspase-6 Monoclonal Antibody (CAB24004)

The Caspase-6 Monoclonal Antibody (CAB24004) is a vital tool for researchers studying caspase-6, a key enzyme involved in apoptosis (cell death) pathways. This monoclonal antibody, developed for use in various research applications, is highly specific to caspase-6 in human samples, providing reliable and accurate results. Caspase-6 is known to play a critical role in various physiological processes, including development, tissue homeostasis, and immune response. Dysregulation of caspase-6 has been implicated in diseases such as neurodegenerative disorders and cancer, highlighting the importance of studying its function.

With its high reactivity and specificity, the Caspase-6 Monoclonal Antibody enables precise detection and analysis of caspase-6 in different cell types, making it an invaluable tool for researchers in the fields of cell biology, apoptosis, and disease research. By understanding the role of caspase-6, researchers can gain insights into disease mechanisms and explore potential therapeutic targets for various conditions.

Product Name:Caspase-6 Monoclonal Antibody
Product Code:CAB24004
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC3212
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Jurkat, MCF7, RAW 264.7, C6
Cellular Location:Cytoplasm

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Immunogen:A synthesized peptide derived from human Caspase-6.
Sequence:Email for sequence
Synonyms:MCH2, CSP-6, caspase-6
Calculated MW:33kDa
Observed MW:35kDa

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