Caspase-6 Monoclonal Antibody (CAB24004)
- SKU:
- CAB24004
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Caspase-6 Monoclonal Antibody (CAB24004)
The Caspase-6 Monoclonal Antibody (CAB24004) is a vital tool for researchers studying caspase-6, a key enzyme involved in apoptosis (cell death) pathways. This monoclonal antibody, developed for use in various research applications, is highly specific to caspase-6 in human samples, providing reliable and accurate results. Caspase-6 is known to play a critical role in various physiological processes, including development, tissue homeostasis, and immune response. Dysregulation of caspase-6 has been implicated in diseases such as neurodegenerative disorders and cancer, highlighting the importance of studying its function.
With its high reactivity and specificity, the Caspase-6 Monoclonal Antibody enables precise detection and analysis of caspase-6 in different cell types, making it an invaluable tool for researchers in the fields of cell biology, apoptosis, and disease research. By understanding the role of caspase-6, researchers can gain insights into disease mechanisms and explore potential therapeutic targets for various conditions.
Product Name: | Caspase-6 Monoclonal Antibody |
Product Code: | CAB24004 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC3212 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, MCF7, RAW 264.7, C6 |
Cellular Location: | Cytoplasm |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
Immunogen: | A synthesized peptide derived from human Caspase-6. |
Sequence: | Email for sequence |
Synonyms: | MCH2, CSP-6, caspase-6 |
Calculated MW: | 33kDa |
Observed MW: | 35kDa |