Caspase-2 Rabbit Monoclonal Antibody (CAB4888)
- SKU:
- CAB4888
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CASP-2
- ICH1
- NEDD-2
- NEDD2
- PPP1R57
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Caspase-2 Rabbit Monoclonal Antibody |
SKU: | CAB4888 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 334-452 of human Caspase-2 (P29594). |
Sequence: | GKNH TQSP GCEE SDAG KEEL MKMR LPTR SDMI CGYA CLKG NAAM RNTK RGSW YIEA LTQV FSER ACDM HVAD MLVK VNAL IKER EGYA PGTE FHRC KEMS EYCS TLCQ QLYL FPGY PPT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; Caspase-2 |
Positive Sample: | Jurkat,HeLa,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytosol, Mitochondrion, Nucleolus, Nucleus |
Calculated MW: | 51kDa |
Observed MW: | 14kDa/48kDa |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 835 |
Clone Number: | ARC0317 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |