Caspase-2 Rabbit Polyclonal Antibody (CAB5724)
- SKU:
- CAB5724
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Caspase-2 Rabbit Polyclonal Antibody |
SKU: | CAB5724 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human Caspase-2 (NP_116764.2). |
Sequence: | KLRL STDT VEHS LDNK DGPV CLQV KPCT PEFY QTHF QLAY RLQS RPRG LALV LSNV HFTG EKEL EFRS GGDV DHST LVTL FKLL GYDV HVLC DQTA QEMQ EKLQ NFAQ LPAH RVTD SCIV ALLS HGVE GAIY GVDG KLLQ LQEV FQLF DNAN CPSL QNKP KMFF IQAC RGDE TDRG VDQQ DGKN HAGS PGCE ESDA GKEK LPKM RLPT RSDM ICGY ACLK GTAA MRNT KRGS WYIE ALAQ VFSE RACD MHVA DMLV KVNA LIKD REGY APGT EFHR CKEM SEYC STLC RHLY LFPG HPPT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; Caspase-2 |
Positive Sample: | Jurkat,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, mitochondrion, nucleolus, nucleus |
Calculated MW: | 51kDa |
Observed MW: | 48kDa |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 835 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |