null

Caspase-14 Rabbit Monoclonal Antibody (CAB9618)

SKU:
CAB9618
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Developmental Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Caspase-14 Rabbit Monoclonal Antibody
SKU:CAB9618
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human Caspase-14 (P31944).
Sequence:GEMV KLEN LFEA LNNK NCQA LRAK PKVY IIQA CRGE QRDP GETV GGDE IVMV IKDS PQTI PTYT DALH VYST VEGY IAYR HDQK GSCF IQTL VDVF TKRK G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:ARCI12; Caspase-14
Positive Sample:SH-SY5Y,Mouse thymus,A375,Mouse stomach,Rat lung,Rat stomach
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:28kDa
Observed MW:17kDa/28kDa/35kDa

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Purification Method:Affinity purification
Gene ID:23581
Clone Number:ARC1661
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Caspase-14 Rabbit mAb (CAB9618) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.

Related Products