CASP8AP2 Rabbit Polyclonal Antibody (CAB15770)
- SKU:
- CAB15770
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | CASP8AP2 Rabbit Polyclonal Antibody |
SKU: | CAB15770 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1733-1982 of human CASP8AP2 (NP_036247.1). |
Sequence: | TVGA FIDL TQDA SSEA KSEG NHPA LAVE DLGC GVIQ VDED NCKE EKAQ VANR PLKC IVEE TYID LTTE SPSS CEVK KDEL KSEP GSNC DNSE LPGT LHNS HKKR RNIS DLNH PHKK QRKE TDLT NKEK TKKP TQDS CENT EAHQ KKAS KKKA PPVT KDPS SLKA TPGI KDSS AALA TSTS LSAK NVIK KKGE IIIL WTRN DDRE ILLE CQKR GPSF KTFA YLAA KLDK NPNQ VSER FQQL MKLF EKSK CR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CED-4; FLASH; RIP25; CASP8AP2 |
Positive Sample: | U-87MG,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus, PML body. |
Calculated MW: | 223kDa |
Observed MW: | 215kDa |
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Purification Method: | Affinity purification |
Gene ID: | 9994 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |