Casp12 Antibody (PACO25500)
- SKU:
- PACO25500
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Casp12 Antibody (PACO25500)
The CASP12 Antibody (PAC025500) is a high-quality polyclonal antibody designed for research involving CASP12, a protein that plays a critical role in immune regulation and inflammatory responses. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it a valuable tool for researchers studying immune-related diseases and mechanisms.CASP12, also known as caspase 12, is a key player in the innate immune response to bacterial infection and endoplasmic reticulum stress. It is involved in the activation of inflammatory pathways and cell death processes, making it a potential target for therapeutic interventions in conditions such as sepsis, autoimmune diseases, and neurodegenerative disorders.
The CASP12 Antibody is validated for use in Western blot applications, enabling researchers to detect and analyze CASP12 protein levels in various cell types and tissue samples. Its reliability and sensitivity make it a preferred choice for studies focusing on immunology, inflammation, and cellular stress responses.By utilizing the CASP12 Antibody in their research, scientists can gain valuable insights into the function and regulation of CASP12, leading to a better understanding of its role in immune modulation and disease pathogenesis. This antibody is a valuable tool for advancing knowledge in the fields of immunology, infectious diseases, and inflammation research.
| Antibody Name: | Casp12 Antibody (PACO25500) |
| Antibody SKU: | PACO25500 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse, Human |
| Immunogen: | Recombinant Mouse Caspase-12 protein (1-92AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Casp12 antibody at 6µg/ml + LO2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48 kDa Observed band size: 48, 75 kDa . |
| Background: | Involved in the activation cascade of caspases responsible for apoptosis execution. |
| Synonyms: | Caspase-12 (CASP-12) (EC 3.4.22.-), Casp12 |
| UniProt Protein Function: | Involved in the activation cascade of caspases responsible for apoptosis execution. |
| UniProt Code: | O08736 |
| NCBI GenInfo Identifier: | 157951684 |
| NCBI Gene ID: | 12364 |
| NCBI Accession: | NP_033938.3 |
| UniProt Secondary Accession: | O08736,Q3TT82, |
| UniProt Related Accession: | O08736 |
| Molecular Weight: | 47,854 Da |
| NCBI Full Name: | caspase-12 |
| NCBI Synonym Full Names: | caspase 12 |
| NCBI Official Symbol: | Casp12Â Â |
| NCBI Protein Information: | caspase-12 |
| UniProt Protein Name: | Caspase-12 |
| Protein Family: | Inactive caspase |
| UniProt Gene Name: | Casp12Â Â |
Related Products
Human Caspase-12 (CASP12) ELISA Kit (HUEB0799)
Rat Caspase-12 (Casp12) ELISA Kit (RTEB0401)
Mouse Caspase-12 (Casp12) ELISA Kit (MOEB0532)
