The CASK Polyclonal Antibody (CAB2501) is a valuable tool for researchers studying the protein CASK, a key player in various cellular processes such as neuronal development, synaptic function, and cancer progression. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications.By targeting the CASK protein, this antibody allows for the detection and analysis of CASK expression in different cell types, providing insights into its role in neurological disorders and cancer.
Understanding the functions and interactions of CASK is essential for unraveling its impact on cell signaling pathways and potential therapeutic targets in diseases such as Alzheimer's and various cancers.Invest in the CASK Polyclonal Antibody (CAB2501) for your research needs and delve deeper into the mechanisms underlying CASK-mediated pathways and their implications in health and disease.
Product Name:
CASK Rabbit Polyclonal Antibody
SKU:
CAB2501
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CASK (NP_001119526.1).
This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8573
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CASK Rabbit pAb (CAB2501) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
