CASK Rabbit Polyclonal Antibody (CAB2501)
- SKU:
- CAB2501
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CASK Rabbit Polyclonal Antibody |
SKU: | CAB2501 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CASK (NP_001119526.1). |
Sequence: | MADD DVLF EDVY ELCE VIGK GPFS VVRR CINR ETGQ QFAV KIVD VAKF TSSP GLST EDLK REAS ICHM LKHP HIVE LLET YSSD GMLY MVFE FMDG ADLC FEIV KRAD AGFV YSEA VASH YMRQ ILEA LRYC HDNN IIHR DVKP HCVL LASK ENSA PVKL GGFG VAIQ LGES GLVA GGRV GTPH FMAP EVVK REPY GKPV DVWG CGVI LFIL LSGC LPFY GTKE RLFE GIIK GKYK MNPR QWSH ISES AKDL VRRM LMLD PAER ITVY EALN HPWL KERD RYAY KIHL PETV EQLR KFNA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CMG; FGS4; LIN2; TNRC8; hCASK; CAGH39; CAMGUK; MICPCH; MRXSNA; CASK |
Positive Sample: | 293T,U-251MG,BxPC-3,22Rv1,NCI-H460,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein. |
Calculated MW: | 105kDa |
Observed MW: | 115kDa |
This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8573 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |