The Casein Kinase 2 Beta Rabbit Monoclonal Antibody (CAB4519) is a versatile tool for researchers studying the protein kinase CK2β, a key regulatory molecule involved in various cellular processes. This high-quality antibody, derived from rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications.CK2β is a critical component of the CK2 holoenzyme, which plays a pivotal role in cell cycle regulation, DNA repair, apoptosis, and cellular signaling pathways. Dysregulation of CK2β has been linked to cancer, neurodegenerative diseases, and other disorders, making it a compelling target for drug development and therapeutic interventions.
By specifically binding to CK2β, this monoclonal antibody enables precise detection and analysis of the protein in a wide range of cell types and experimental settings. Its reliability and accuracy make it an invaluable asset for studies in cell biology, molecular biology, and drug discovery, offering valuable insights into the intricate mechanisms governed by CK2β in health and disease.
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1460
Clone Number:
ARC1069
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Casein Kinase 2 beta (CSNK2B) (CSNK2B) Rabbit mAb (CAB4519) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
