The CARD14 Polyclonal Antibody (CAB16569) is a valuable tool for research focused on the CARD14 protein, which is involved in the regulation of inflammatory and immune responses. This antibody, derived from rabbit sources, is specifically reactive with human samples and has been validated for use in Western blot applications. By targeting the CARD14 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in immunology, dermatology, and inflammatory diseases.CARD14 is a key player in the signaling pathways that control immune and inflammatory responses in the skin, making it a target of interest in research on conditions like psoriasis and inflammatory skin disorders.
Understanding the role of CARD14 in these processes is essential for developing targeted therapies that can effectively manage inflammatory skin conditions. The use of the CAB16569 Polyclonal Antibody provides researchers with a reliable tool to further explore the functions of CARD14 and its implications in disease pathology.
Product Name:
CARD14 Rabbit Polyclonal Antibody
SKU:
CAB16569
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human CARD14 (NP_001244899.1).
This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
79092
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CARD14 Rabbit pAb (CAB16569) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
