CARD11 Rabbit Monoclonal Antibody (CAB9652)
- SKU:
- CAB9652
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CARD11 Rabbit Monoclonal Antibody |
SKU: | CAB9652 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1055-1154 of human CARD11 (Q9BXL7). |
Sequence: | EAGI GCTR DLIK SNIY PIVL FIRV CEKN IKRF RKLL PRPE TEEE FLRV CRLK EKEL EALP CLYA TVEP DMWG SVEE LLRV VKDK IGEE QRKT IWVD EDQL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PPBL; BENTA; BIMP3; IMD11; CARMA1; IMD11A; CARD11 |
Positive Sample: | K-562,Raji,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane raft. |
Calculated MW: | 133kDa |
Observed MW: | 150kDa |
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Purification Method: | Affinity purification |
Gene ID: | 84433 |
Clone Number: | ARC1680 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |