The CARD10 Polyclonal Antibody (CAB7368) is a vital tool for researchers studying the CARD10 protein, which plays a crucial role in various cellular processes, including immune and inflammatory responses. This antibody, derived from rabbit immunization, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.CARD10, also known as caspase recruitment domain-containing protein 10, is a key component of signaling pathways involved in immune cell activation and inflammation. Dysregulation of CARD10 has been linked to the development of inflammatory diseases and certain types of cancer, highlighting its importance in disease pathogenesis.
By targeting the CARD10 protein, researchers can gain valuable insights into its function and potential therapeutic applications. The use of the CAB7368 antibody allows for the precise detection and analysis of CARD10 in various cell types, paving the way for advancements in immunology and cancer research.Understanding the role of CARD10 in immune signaling pathways is essential for the development of novel treatments for inflammatory disorders and cancer.
Product Name:
CARD10 Rabbit Polyclonal Antibody
SKU:
CAB7368
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 863-1032 of human CARD10 (NP_055365.2).
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).
Purification Method:
Affinity purification
Gene ID:
29775
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using CARD10 Rabbit pAb (CAB7368) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
