The Carboxypeptidase A1 Polyclonal Antibody (CAB3803) is specially developed for researchers studying Carboxypeptidase A1, an enzyme involved in the breakdown and regulation of peptides. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the Carboxypeptidase A1 protein, this antibody enables the detection and analysis of this enzyme in various cell types, making it an excellent tool for studies in enzymology and protein research.Carboxypeptidase A1, also known as pancreatic carboxypeptidase, plays a crucial role in the digestion and metabolism of proteins by cleaving off amino acids from the C-terminal end of peptides.
Understanding the function and regulation of Carboxypeptidase A1 is essential for advancing research in fields such as gastrointestinal physiology, metabolism, and pancreatic disorders. This antibody provides a valuable tool for investigating the expression and activity of Carboxypeptidase A1 in both normal and diseased tissues, offering insights into its potential role in various health conditions.
Product Name:
CPA1 Rabbit Polyclonal Antibody
SKU:
CAB3803
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CPA1 (NP_001859.1).
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.
Purification Method:
Affinity purification
Gene ID:
1357
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CPA1 antibody (CAB3803) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
