The CAPZB Polyclonal Antibody (CAB8106) is a valuable tool for researchers studying CAPZB, a protein involved in actin filament capping and cytoskeleton organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the CAPZB protein, this antibody enables the detection and analysis of CAPZB in different cell types, making it ideal for research in cell biology and molecular biology.CAPZB is a key regulator of actin dynamics and plays a crucial role in cellular processes such as cell motility, membrane trafficking, and cell division.
Dysregulation of CAPZB has been implicated in various diseases, including cancer and neurological disorders. By studying the function and expression of CAPZB, researchers can gain insights into its role in these diseases and potentially identify novel therapeutic targets for future drug development.Overall, the CAPZB Polyclonal Antibody (CAB8106) offers researchers a reliable and sensitive tool for investigating the role of CAPZB in cellular processes and disease pathology, paving the way for advancements in biomedical research and drug discovery.
Product Name:
CAPZB Rabbit Polyclonal Antibody
SKU:
CAB8106
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human CAPZB (NP_004921.1).
A-431,THP-1,HeLa,Mouse brain,Mouse testis,Mouse spleen,Rat small intestine
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, cytoskeleton, myofibril, sarcomere.
Calculated MW:
31kDa
Observed MW:
31kDa
This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method:
Affinity purification
Gene ID:
832
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CAPZB antibody (CAB8106) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
