The CAPZA3 Polyclonal Antibody (PACO15925) is a valuable tool for researchers studying the CAPZA3 protein, an important component of the actin cytoskeleton. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CAPZA3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology, molecular biology, and cancer research.CAPZA3 is involved in actin filament capping, which plays a crucial role in cell motility, division, and shape maintenance.
Dysregulation of the actin cytoskeleton has been linked to various diseases, including cancer and developmental disorders. Therefore, understanding the function of CAPZA3 can provide valuable insights into these conditions and may lead to the development of targeted therapies.Overall, the CAPZA3 Polyclonal Antibody is a reliable tool for researchers seeking to elucidate the role of CAPZA3 in cellular processes and disease mechanisms. Its high specificity and sensitivity make it an essential reagent for advancing knowledge in the field of cell biology and beyond.
Antibody Name:
CAPZA3 Antibody (PACO15925)
Antibody SKU:
PACO15925
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human CAPZA3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO15925(CAPZA3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO15925(CAPZA3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes an actin capping protein, one of the F-actin capping protein α subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of α and β subunits. This protein may be important in determining sperm architecture and male fertility.
Synonyms:
capping protein (actin filament) muscle Z-line, α 3
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility. [provided by RefSeq, Jul 2008]
